To identify comorbidities associated with opioid addiction, and opportunities for integrated approaches for prevention and treatment among American Indian and Alaska Native communities.

To describe strengths-based approaches and other unique cultural considerations (e.g., historical trauma and enculturation) in the context of protective factors, risks, and resilience.

Understanding what other conditions are associated with opioid addiction (e.g., alcohol abuse, anxiety, depression, domestic violence, suicide ideation, trauma, and unemployment)

Destigmatizing mental illness and opioid addiction

Promoting resilience- and strengths-based approaches utilizing community capacity, Indigenous culture, and social networks.